The antitoxic effect of cell juice of the Siberian fir was studied in the laboratory conditions in the Research Institute of Hygiene (Novosibirsk). Against the background of poisoning of mice with ethanol, potassium chloride and sodium nitroprusside, a significant reduction of toxic effect of the above agents was revealed in experimental animals which were introduced the fir extract. The introduction increased the percentage of surviving animals when intoxicating them with the above listed agents in lethal doses.