Clinical studies of fir cell juice, conducted with the participation of children with the attention deficit and hyperactivity disorder, confirmed its positive influence on the neurological status. Against the background of treatment with fir cell juice, the increase of attention, the reduction of impulsiveness and irritability, improvement of dynamics of neuropsychological manifestations was observed in children.
Siberian State Medical University, Chair of Biochemistry (Tomsk) Children City Hospital No. 2 Children Polyclinic No. 2 (Tomsk) As a result of treatment with fir extract, improvement in the neurological status were observed in children with ADHD. In addition to reduction of the excessive motor activity and impulsiveness, increase of attention, there was reduction of extrapyramidal disorders that manifested themselves as some rigidity in drawing and writing, pyramidal disorders in the form of brisk tendon reflexes, symptoms of peripheral cervical insufficiency and cerebellar signs in the form of mild ataxia.
Test results by using the questionnaire of J. Swanson revealed that, after a course of fir extract, such deviations as inattention and inattention without hyperactivity disappeared in 9% and 5% of children.
Impulsiveness indicators and oppositional disorders revealed a more significant progress: 26% and 33%, respectively. Under the influence of the fir extract, the severity of impulsiveness decreased by 34%, that of oppositional disorders - by 40%, inattention - 13%, inattention without hyperactivity - 14%. There was a significant positive influence of the fir extract on the processes of lipid peroxidation. Catalase activity increased by 40% after a course of the extract. The concentration of MDA was lower by 32.5% compared to the values measured before the therapy.
The use of the Siberian fir extract for internal application in the scheme of treatment of children with ADHD is accompanied by the improvement of dynamics of neuropsychological manifestations and the state of oxidative processes in children with ADHD, which is due to its antioxidant effect.