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ANTYHYPOXIC EFFECT OF CELL JUICE OF FIRST


The pre-clinical study of the antihypoxic effect of cell juice of the Siberian fir was conducted in the Research Institute of Hygiene (Novosibirsk) in laboratory mice.
Under conditions of oxygen deficiency in mice, the introduction of the extract increased the life time to 32% compared with the control group receiving water. The hypoxic exposure caused a stress reaction, as in immobilization stress. The water extract protected internal organs, restored the content of white blood cells that was reduced against the background of hypoxic stress, cells of bone marrow, spleen, and thymus.

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ANTIOXIDANT PROPERTIES OF CELL JUICE OF FIRS

Studies of the antioxidant properties of cell juice of firs were conducted with the participation of children from the radiation-tainted areas of Tomsk Oblast, as well as children with the attention deficit and hyperactivity disorder. The results of the studies reliably confirmed the reduction of the level of toxic products and the increase of catalase activity against the background of administration of cell juice.

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ANTI-TOXIC EFFECT OF CELL JUICE OF FIRS

The antitoxic effect of cell juice of the Siberian fir was studied in the laboratory conditions in the Research Institute of Hygiene (Novosibirsk). Against the background of poisoning of mice with ethanol, potassium chloride and sodium nitroprusside, a significant reduction of toxic effect of the above agents was revealed in experimental animals which were introduced the fir extract. The introduction increased the percentage of surviving animals when intoxicating them with the above listed agents in lethal doses.

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ANALGESIC EFFECT OF FIR CELL JUICE

A preclinical study of anaesthetic properties of cell juice of the Siberian fir was conducted at the Research Institute of Hygiene in Novosibirsk.
The introduction of the fir extract to mice makes the time of their stay on the hot plate more than 2 times longer. When the 0,75% solution of acetic acid is injected intraperitoneally to animals, the fir extract makes the number of pain cramps 2.8 times lower and the time till the first cramps 2 times longer.

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POLYPRENOLS AND CHRONIC ALCOHOLISM

Clinical study.
Patients suffering with alcoholism of stage 2 took part in the study. After 30 days of treatment with polyprenols in combination with the infusion detoxication, 10% of patients recovered completely, 80.6% passed from the severe stage of the disease to a lighter one. The effect of the treatment already started on the 15th day, on average. As a result it was found that the inclusion of polyprenols in the course of treatment of alcoholism leads to a rapid regress of the abstinence syndrome, reduction of depression and polyneuropathic disorders. Polyprenols are well tolerated and do not cause side effects.

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POLYPRENOLS IN TREATING ALCOHOLIC AND NARCOTIC INTOXICATION

Clinical study.
The study was conducted with the participation of 60 people with alcoholic and narcotic intoxication complicated by hepatitides and HIV infection. Half of the test subjects took the traditional basic therapy, the other half was given polyprenols. Polyprenols showed their effectiveness on the 15th day of therapy already, with the process of recovery from the abstinence syndrome was 3-7 days only. Normalization of all indicators of blood and urine was faster than that of the group taking the basic therapy. In addition, in the therapy of polyprenols, a significant improvement of the function of the central nervous system was noted.

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POLYPRENOLS IN THE TREATMENT OF CHRONIC ALCOHOLISM

Clinical study
90 patients suffering from chronic alcoholism took part in the study. 60 of them received polyprenols, and the other 30 underwent a course of basic therapy. After 30 days of treatment, 66% of patients taking polyprenols had a significant positive dynamics that manifested itself in the improvement of the brain functions. These changes were recorded using electroencephalography. Patients with the basic therapy had improvement only in 23% of cases and were insignificant.

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ANTI-INFLAMMATORY EFFECT OF FIR CELL JUICE

The experimental research of the effect of cell juice of the Siberian fir on inflammatory processes was carried out in laboratory conditions in the Research Institute of Hygiene in Novosibirsk. Acute inflammation in experimental animal was modelled by introducing carrageenin. In animals, which were previously introduced the fir extract, the inflammatory edema was 2 times less than that of the control animals which were not introduced the fir extract. The content of white blood cells also restored, that was increased against the background of the inflammation. The preparation exerted a protective effect on the internal organs exposed to inflammatory stress.

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